applications
that fit your needs for multiple industries for various use cases

Extract value from your data across various fields of applications

unlimited fields of applications

Our insilico solutions are flexible enough to extract value from your data across various applications.

multiple industries

Biotech, Pharmaceuticals, Nutrition, Cosmetics, Home and Personal Care, Retail, Agritech, Chemicals...

various departments

Research & Development, Sales, Marketing, Logistics, Human Resources, Business Intelligence...

Diverse Use cases

Biomarker Discovery, Structural Alert Detection, Product Claims, Profiling, Chemical Safety...

FormulAtion:
cosmetics and raw materials

Formulation is the art of mixing synthetic or natural raw materials in order to create a final product, characterised by distinct functional properties and that fits the specifications. Therefore, formulation is a key step involved in various material processing industries (cosmetics, agrifood, pharma, adhesives, painting, detergents, concrete,etc…) from upstream (raw material synthesis) to downstream industries in touch with customers (makeup, nutrition).

Formulation is a subject of concern for the Chemical industry because they create active ingredients as well as formulation auxiliaries, which are marketed more for their functional attributes (thickener, UV filter , dye, moisturiser) than their chemical properties (molecular structure, purety, etc…). Downstream industries that formulate for the final customer need to create even more complex formulas. Indeed, diverse raw materials are associated in order to design a ready-to-use product which possesses specific commercial properties and performances. In the end, the formulation revolves around all the application of chemical, natural or synthetic compounds. The goal is to find the best compromise between performance, cost and safety.

QUIID[HUB] helps you create well balanced formulas by giving you the opportunity to reveal new insight, to make smart formulation and also to predict the properties (physical or even hedonic) of your final product. Using QUIID[HUB] for formulation provides you with a strong support to fit your product specifications and to develop innovative formulas in an eco-conception approach.

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use quiid[HUB] for formulation

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packaging:
cosmetics, Nutrition, pharma

Packaging processes regroup all the aspects of conditioning and packing industrial products. Their main functions are to contain, protect, carry, and commercially identify items.

Nowadays, it has become critical to consider the ecoresponsibility and ecotoxicology sides of the packaging processes. Indeed, on top of being efficient and safe, the selected materials should be biodegradable, and their production/recycling processes have to be done in an ecological way (waste recovery, reducing carbon footprint, etc…).That is why, to tackle these new problematics, compagnies design innovative packaging made of new materials, meaning that sometimes the functional and the toxicological properties of the package remains largely unknown. In addition, the interactions between products and their packaging can be detrimental to quality and/or safety.

By screening packaging databases, QUIID[HUB] gives you the opportunity to predict your package specifications and the potential product/package emerging properties (ex: stability, degradation, peremptory interaction). Using QUIID[HUB] all along the packaging assessment provides you with solid support to quickly assess whether your final products meet your requirements and specifications.

use quiid[HUB] for packaging

chemical toxicology:
cosmetics & pharma safety

During the development of novel pharmaceuticals drugs or cosmetics, hazard assessment is a critical step. The development of chemicals now requires scientists to fill data-gap. For the formulators to tackle this problematic, they must use a pluridisciplinary approach that respect the regulations and recommendations of authoritative bodies. Besides, animal testing has been strongly reduced and classical investigation (in vitro, in cellulo) are not sufficient by themselves for toxic assessment anymore. Furthermore, because multiplying classical experimentation is time and money consuming, we created a decision-support system named QUIID[CHEM] for toxic hazard assessment.

QUIID[CHEM] aims at optimising your development process by providing a decision-support system, which helps you to shortlist the best chemical candidates during read-across processes. QUIID[CHEM] helps scientists to early predict structural alerts related to toxic properties or any other endpoints (e.g., sensitisation, carcinogenic, mutagenic, or metabolic properties…). The targeted properties of the queried chemicals are predicted using datamining methodologies applied to chemical databases (public and/or private databases). Our predictions allow you to anticipate toxic issues along the drug design phase, leading you to scale up your productivity.

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Related publications :

Jean-Philippe Métivier, Alban Lepailleur, Aleksey Buzmakov, Guillaume Poezevara, Bruno Crémilleux, Sergei Kuznetsov, Jérémie Le Goff, Amédéo Napoli, Ronan Bureau, Bertrand Cuissart: Discovering structural alerts for mutagenicity using stable emerging molecular patterns. Dans: Journal of Chemical Information and Modeling, 0 (ja), p. null, 2015, (PMID: 25871768).

Bertrand Cuissart, Guillaume Poezevara, Bruno Cremilleux, Alban Lepailleur, Ronan Bureau: Emerging Patterns as Structural Alerts for Computational Toxicology. Dans: Chapman and Hall/CRC, 2012, ISBN: 978-1-4398-5432-7, (0).

Sylvain Lozano, Guillaume Poezevara, Marie-Pierre Halm-Lemeille, Elodie Lescot-Fontaine, Alban Lepailleur, Ryan Bissell-Siders, Bruno Crémilleux, Sylvain Rault, Bertrand Cuissart, Ronan Bureau: Introduction of Jumping Fragments in Combination with QSARs for the Assessment of Classification in Ecotoxicology. Dans: Journal of Chemical Information and Modeling, 50 (8), p. 1330-1339, 2010, (PMID: 20726596).

for chemicals use Quiid[CHEm]

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metabolomics:
biomarkers identification

Metabolomics, the science of metabolites analysis, is an emerging and promising technology that aims at identifying complex metabolic signatures and pathways. Metabolome profiling contributes towards a better understanding a human physiology by giving us a functional readout of cellular biochemistry. That is why the identification of specific biochemical fingerprints is a key step to tackle common problematics within the (pre)clinical studies and healthcare industry (e.g., biomarkers for diagnostics, treatment’s response, precision medicine…).

Historically, small numbers of metabolites have been used to diagnose complex metabolic diseases as well as monogenic disorders such as inborn errors of metabolism. However in the last decades, emerging technologies (such as proteomic methodologies or high througtput sequencing) have continuously generated complex and considerable amount of data about the metabolome, meanwhile the solutions for analysing those datasets are not efficient as well.

QUIID understands your needs and provides you with solutions to tackle metabolomics problematics. We are able to apply our technology on any subset of metabolic data to unveil hidden correlations between variables (e.g., metabolite interactions, dose effect, pronostical model, pathfinding). QUIID helps you to deeply analyse your existing metabolomics data, and also provides a heavy support and fully understandable outputs. 

Related publications :

Guillaume Poezevara, Sylvain Lozano, Bertrand Cuissart, Ronan Bureau, Pierre Bureau, Vincent Croixmarie, Philippe Vayer, Alban Lepailleur: A Computational Selection of Metabolite Biomarkers Using Emerging Pattern Mining: A Case Study in Human Hepatocellular Carcinoma. Dans: Journal of Proteome Research, 0 (0), p. null, 2017, (PMID: 28447453).

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proteomic INVESTIGATION:
make it easier & faster

The main objective of proteomic is to identify and quantify the proteins contained in a biological sample to obtain functional data, in order to localise and/or identify protein partners or protein binding sites. These data allow us to better understand the molecular mechanisms underlying specific cellular functions. Helped with mass spectrometry methologies, the emergence of proteomics large-scale analysis on multiple and various biological specimens, now generate gigantic quantities of data. Moreover, this data rising phenomenon is intensified by the fact that the proteome could be considered as a dynamic and complex entity.

QUIID understands your aims and provides solutions to tackle issues coming from the proteomics field. Indeed, because proteomics studies quickly generate a large volume of data, their analyses require a computational-based support to improve scientist’s efficiency. QUIID understands your needs and provide expert data mining solutions buy identifying new hidden correlations between the different characteristics obtained from your proteomic experiments (redundant protein partners, binding affinity, comparison to treated condition). Our solutions allow you to deeply investigate signaling pathway (linear cascade, crosstalks, etc…), biomarkers validation (early pathological detection) or assess treatment delivering/efficacy.

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your activity

No matter your industry, activities and applications, do not hesitate to contact us to find out how we can help you exploit the full potential of your data thanks to our in silico solutions.

We’re looking forward to hearing from you!